FIRST Numerics, Bringing numerics to Life ®
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About FIRST Numerics
 
Our mission statement
 
 
 
FIRST Numerics Ltd was established to answer the increasing demand for highly specialised numerical simulations for various industries such as medical devices / healthcare products / tissue engineering / automotive / transport / defence and virtual reality.
Our services can be tailored to provide solutions to a wide range of challenges and engineering problems in the area of:

mathematical / numerical modelling in biomechanics and biomedical engineering.

We have the ability to develop software coding for specialised applications in biomechanical and biomedical engineering which are not available in standard commercial finite element codes. This facility is of particular interest to companies who wish to access state of the art software to enable the development and assessment of new or improved devices.

 
"Providing high-standard customised computational solutions to engineering problems involving the simulation of the behaviour of biological tissues and structures."

Although our mission is simple, the technologies and knowledge bases involved are not !!!

 

 
What FIRST Numerics can bring to you Partnerships
 
 
 
 
FIRST Numerics' staff have over 30 years experience in numerical techniques (Finite Element Methods / CFD / Optimisation / Homogenisation), applied mechanical and biomedical engineering, non-linear mechanics, constitutive modelling and biomechanics. Some of our consultants are activey involved in academic research and are international experts in their field.

Projects have included assessment of implant devices such as ceramic hip components, dental implants, assessment and design analyses of tibia and hip prostheses (interface analysis), polymerisation of dental cements, finite element analysis of the knee joint imbalanced by ligamentous structures, homogenisation of micromechanical properties of implant interfaces and development of dedicated contact model and the development of constitutive laws for soft tissue.

Based on our highly specialised skills, research knowledge and experience in solving industrial problems, we are confident that we could save your company time and effort. We would provide you with complete computational solutions especially customised to your specific project requirements, taking into consideration the finite element package you are already using in your company.

Whatsmore it would be a pleasure for us to work with your team on challenging and exciting projects... as well as those projects currently causing a headache!!!

*isotropy of mechanical properties: identical properties in all directions within the material

FIRST Numerics Ltd has established a partnership with Simpleware Ltd (Exeter, UK), a very dynamic company offering software (ScanIP™, ScanFE™) and services to generate volumetric finite element meshes from 3D scan data. Simpleware and FIRST Numerics can therefore provide complete FEA and CFD solutions in a very cost-effective manner.



FIRST Numerics Ltd
works in partnership with the School of Dentistry, Wales College of Medicine, Cardiff University, Cardiff which is one of the UK leading research-teaching institutions. This unique combination of expertise offers a "one stop shop" for medical device and pharmaceutical companies which can benefit from advanced computational analyses (pre-clinical assessment) and high calibre clinical research.

 
Understanding the mechanics of biological tissues Why FIRST Numerics provides customised solutions
 
 
 
 
A sound knowledge of non-linear Finite Element Methods (or CFD) is generally not enough to perform realistic numerical simulations as far as the human body is concerned. An indepth knowledge of the mechanical behaviour of biological tissues is crucial as is information about physiological and abnormal loading conditions.
Unlike traditional engineering creations (a metal bridge, the fuselage of an aircraft, a cell phone, etc..) made of traditional engineering materials (steel, alloys, plastics, etc…), the human body is a highly complex system that hosts mechanical, thermal, electrical, chemical and cellular processes.

One of the challenges of the bioengineering area is to characterise the mechanical properties of each constituent of the human body (bones, ligaments, tendons, cartilage, skin, arteries, muscles, etc…) before addressing the way they interact with medical devices and the external environment. All these biological materials have a very complex behaviour: they are time-dependent, highly nonlinear, can sustain large deformations and are sensitive to internal or external conditions (hydratation...). Last, but not the least, they are living materials which are constantly evolving.

For example, performing numerical simulations of the behaviour of soft tissues (arteries, ligaments, cartilage, etc...) by assuming isotropy of the mechanical properties* is generally a very restrictive framework which provides erroneous results compared to the real physiological conditions. A computer model does not pretend to be the exact copy of the reality, indeed it could be said that the end for the quest to the Grail of Computational Biomechanics is still far ahead of us !!!. However, the fibrous nature of soft tissues is a key element in their mechanical behaviour and should be integrated into the modelling process. Failure to do so can be prevented but requires specialised knowledge and software applications.

Often a cause for frustration is the use of the material library of standard commercial finite element software packages for biomechanical applications. From our research experience we know all too well that the only solution to performing state-of-the-art biomechanical simulations is to develop specific biological material models. This not only involves the programming of the model into the numerical code but also the development of constitutive equations and the calibration with relevant experimental data. Our work is mainly based on analytical and numerical modelling but we have very good access to experimental data on biological tissues via our network of research associates operating in top class experimental facilities. Our projects are generally internationally based with work being carried out with overseas partners at industrial and academic research centres.

We have considerable experience of working directly with clinicians and biologists and have built upon our skills in order to bridge the gap that exists between the various disciplines involved, especially in terms of communication. If we want to deliver efficient solutions to real-life problems there is great benefit to be had from talking to one another and pooling our separate expertise.

 

 

   FIRST Numerics Ltd, Cardiff Medicentre, Heath Park, Cardiff CF14 4UJ, United Kingdom
   Tel: +44 (0)2920682162, Fax: +44 (0)2920682161, Email:
info@firstnumerics.com
   © 2002-2007, FIRST Numerics Ltd. All rights reserved.